Neurogenic pulmonary edema develops within a few hours after a neurologic insult, and diagnosis requires exclusion of other causes of pulmonary edema (eg, high-altitude pulmonary edema). • Signs of NPE in computed tomography (CT) examinations were retrospectively assessed in patients admitted for acute seizures. The mechanism of neurogenic pulmonary edema in epilepsy ... sive seizure-related outpouring of central sympathetic activity, which leads to an increase in pulmonary vascular resistance [13, 14]. The ris ien intracranial pressure, i whics oftehn observed in conjunction with neurogenic pulmonary edema (Ducke anr d Simmons, 1968; Simmons et al., 1968), may be a requirement for th developmene t of pulmonary edema. The diagnosis of neurogenic pulmonary edema is based on the occurrence of edema after a neurologic event/insult and the exclusion of other plausible causes. Introduction: Neurogenic pulmonary oedema (NPE) is a very rare complication of epileptic seizures, which could potentially increase mortality. drostatic pressure in the development of neurogenic pulmonary edema. Acute pulmonary edema following significant injury to the central nervous system is known as neurogenic pulmonary edema (NPE). Neurogenic pulmonary edema (NPE) is an underdiagnosed clinical entity. Neurogenic pulmonary oedema as a rare complication of epileptic seizures Abstract Introduction: Neurogenic pulmonary oedema (NPE) is a very rare complication of epileptic seizures, which could potentially increase mortality. Material and methods: The case of a 66-year-old male patient with NPE caused by repeated epileptic seizures is reported. Intracranial hypertension elic- Neurogenic pulmonary edema (NPE) may be involved in seizure-related complications and SUDEP. Neurogenic pulmonary edema (NPE) is a non‐cardiogenic pulmonary edema that is caused by an acute central nervous system injury and usually develops rapidly after an injury. Neurogenic pulmonary edema may be a complication of the terminal phase of cerebral tumors. We report a case of acute pulmonary oedema after a tonic clonic seizure. Neurogenic pulmonary edema is also an increasingly recognized complication of pediatric encephalitis with Enterovirus-71 (Hand, foot, and mouth disease) . In patients with epilepsy mortality due to accidents, asphyxia, cardiac arrhythmias or postictal neurogenic pulmonary oedema (NPO) is twice as high as in the general population. Although several episodes of NPE resolve spontaneously, the condition may … NPE has been documented in patients with cere-bral hemorrhage, subarachnoid hemorrhage, cerebral thrombosis, acute open and closed Reported etiologies of neurogenic pulmonary edema are listed in the table . Commonly seen after significant neurological trauma, NPE has also been described after seizure. Rapid resolution of pulmonary oedema is well documented by X-ray and computed tomography images. The diagnosis 'tonic clonic seizure' is frequently established by emergency physicians on scene. A 21-year-old man had a seizure episode following cranioplasty. ... seizures, and 1% occurred after cerebral trauma. We report two cases of NPE and review the literature on NPE cases reported since 1990. The aim of this study is to explore the exact mechanism of epilepsy-induced NPE. Neurogenic pulmonary edema (NPE) is characterized by the development of pulmonary edema within minutes to hours of a significant central nervous system (CNS) insult, often resolving spontaneously within 24–48 h [1,2,3].Febrile seizures (FS) is the most common convulsive event, affecting 2–5% of children younger than 60 months [4,5,6,7].The majority of FS cases follow a … Neurogenic pulmonary edema is an etiological subtype of non-cardiogenic pulmonary edema, classified as a subtype of the acute respiratory distress syndrome by the Berlin definition.. Epileptic seizures — Among all patients with epilepsy the occurrence of NPE is rare. Its pathophysiology is multifactorial but largely unknown. While many pathogenic theories have been proposed, the exact mechanism remains unclear. 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